The Honeywell Lyric seems to be yet another thermostat replacement with no boiler fine-control or TRV communication unlike their upmarket evohome system.
The Conrad FHZ1000 (AKA ELV and eQ-3) uses the FS20 automation system and can control a large number or TRVs. I believe this is the same interface used by OpenTRV. A CUL dongle running culfw will also control a number of TRVs. There’s also a webinos project that also uses this protocol.
The Register published this article in June 2014 with a round-up of the top systems available. It is in four parts and covers Apple’s new HomeKit framework, Heatmiser Wi-Fi thermostat, Hive, Google’s Nest, Tado and nCube.